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Results 1 - 10 of 26 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1a + H2O cleavage sites are Glu1430/Gly and Glu1452/Ser equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1a + H2O ORF1a can be cleaved following two alternative pathways. In the majority nsp3-8 precursors are cleaved at the nsp4/5 site yielding nsp3-4 and nsp5-8. The latter product is then cleaved at nsp7/8 only. In the alternative proteolytic cascade the nsp4/5 site remains uncleaved while the nsp5/6 and nsp6/7 sites are processed. nsp3-8 has to interact with cleaved nsp2 to allow processing of the nsp4/5 junction, when nsp2 cofactor is absent the alternative pathway is used equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1a protein + H2O - equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1a protein + H2O nsp4 and an unidentified protease is responsible for the cleavage sites nsp2/3, nsp3/4, nsp4/5 and nsp5/6 in the ORF1a protein equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1a protein + H2O - equine arteritis virus Bucyrus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1ab + H2O cleavage sites are the junctions at nsp3/4, Nsp4/5, 2 internal nsp5 sites, nsp5/6, p80/p50, p50/p26, p26/p12, enzyme cleaves between Glu and Gly, Glu and Ser or Glu and Lys equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1ab + H2O cleavage sites are the junctions at nsp3/4, Nsp4/5, 2 internal nsp5 sites, nsp5/6, p80/p50, p50/p26, p26/p12, enzyme cleaves between Glu and Gly, Glu and Ser or Glu and Lys equine arteritis virus Bucyrus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1b + H2O protein is processed by nsp4 serine protease equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1b + H2O protein is processed by nsp4 serine protease at the following sites: nsp9/10 i.e. p80/p50, cleavage occurs between Glu2370 and Ser, nsp10/11 i.e. p50/p26, cleavage occurs between Gln2837 and Ser, nsp11/12 i.e. nsp26/p12, cleavage between Glu3056 and Gly equine arteritis virus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.114arterivirus replicase ORF1b + H2O protein is processed by nsp4 serine protease equine arteritis virus Bucyrus ? - ?
Results 1 - 10 of 26 > >>