EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.1.6.9 | 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid-beta-(1-3)-GalNAc4SO3--beta-(1-4)-glucuronic acid-2-sulfate-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3- + H2O |
removal of two sulfate groups |
Proteus vulgaris |
sulfate + 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid-beta-(1-3)-GalNAc-beta-(1-4)-glucuronic acid-2-sulfate-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc |
- |
? |
3.1.6.9 | 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid-beta-(1-3)-GalNAc6SO3--beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3- + H2O |
removal of two sulfate groups |
Proteus vulgaris |
sulfate + 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid-beta-(1-3)-GalNAc6SO3--beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc |
- |
? |
3.1.6.9 | 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3- + H2O |
removal of one sulfate group |
Proteus vulgaris |
sulfate + 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc |
- |
? |
3.1.6.9 | 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid2SO3--beta-(1-3)-GalNAc6SO3--beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3- + H2O |
removal of two sulfate groups |
Proteus vulgaris |
sulfate + 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid2SO3--beta-(1-3)-GalNAc6SO3--beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc |
- |
? |
3.1.6.9 | 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid2SO3--beta-(1-3)-GalNAc6SO3--beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc4SO3- + H2O |
removal of one sulfate group |
Proteus vulgaris |
sulfate + 4-deoxy-alpha-L-threo-hex-4-enepyranosyluronic acid2SO3--beta-(1-3)-GalNAc6SO3--beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc6SO3-beta-(1-4)-glucuronic acid-beta-(1-3)-GalNAc |
- |
? |
3.1.6.9 | 4-deoxy-alpha-L-threo-hex-4-enepyranuronosyl-(1->3)-beta-D-GalNAc(4-O-sulfate)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal(4-O-sulfate)-(1->3)-beta-D-Gal-(1->4)-D-Xyl + H2O |
- |
Proteus vulgaris |
sulfate + 4-deoxy-alpha-L-threo-hex-4-enepyranuronosyl-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-Xyl |
- |
? |
3.1.6.9 | more |
the enzyme acts preferentially on an ester sulfate on the C4 position of the GalNAc residue at the reducing end under mild incubation conditions, but also releases a sulfate group under harsh conditions from the C4 position of the GalNAc residue at the internal positions of the hexasaccharide chains, unless the GalNAc residue has another ester sulfate on its C6 position |
Proteus vulgaris |
? |
- |
? |
3.1.6.9 | more |
the enzyme breaks down one of the products of the chondroitin lyase reaction. An upstream insertion mutant that has no detectable chondro-4-sulfatase activity is still able to grow on chondroitin sulfate, although the rate is slower than that of the wild type |
Bacteroides thetaiotaomicron |
? |
- |
? |