EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.1.3.B4 | 1,2-dihexadecanoyl-sn-glycero-phospho-1-D-myo-inositol 4-phosphate + H2O |
- |
Arabidopsis thaliana |
1,2-dihexadecanoyl-sn-glycero-phospho-1-D-myo-inositol + phosphate |
- |
? |
| 3.1.3.B4 | more |
Sac1, a phosphoinositide lipid phosphatase, removes the phosphate residue from the inositol head group of phosphatidylinositol-4-phosphate |
Saccharomyces cerevisiae |
? |
- |
? |
| 3.1.3.B4 | more |
SacI is in complex with Vps74, a phosphatidylinositol 4-kinase effector |
Saccharomyces cerevisiae |
? |
- |
? |
| 3.1.3.B4 | more |
Vps74 (a PI4K effector required to maintain residence of a subset of Golgi proteins) binds directly to the catalytic domain of Sac1. Vps74 is a sensor of Pt¬dIns4P level on medial Golgi cisternae that directs Sac1-mediated dephosphosphorylation of this pool of PtdIns4P |
Saccharomyces cerevisiae |
? |
- |
? |
| 3.1.3.B4 | more |
Sac1 is active on PI(5)P, PI(4)P, PI(3)P, with low activity on PI(3,5)P2, and with no activity on other phosphoinositides |
Saccharomyces cerevisiae |
? |
- |
? |
| 3.1.3.B4 | more |
the enzyme shows no activity on either phosphatidylinositol 4,5-bisphosphate or phosphatidylinositol 3,4,5-triphosphate |
Mus musculus |
? |
- |
? |
| 3.1.3.B4 | phosphatidylinositol 4-phosphate + H2O |
- |
Drosophila melanogaster |
phosphatidylinositol + phosphate |
- |
? |
| 3.1.3.B4 | phosphatidylinositol 4-phosphate + H2O |
- |
Homo sapiens |
phosphatidylinositol + phosphate |
- |
? |
| 3.1.3.B4 | phosphatidylinositol 4-phosphate + H2O |
- |
Saccharomyces cerevisiae |
phosphatidylinositol + phosphate |
- |
? |
| 3.1.3.B4 | phosphatidylinositol 4-phosphate + H2O |
preferred substrate |
Saccharomyces cerevisiae |
phosphatidylinositol + phosphate |
- |
? |
