EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.1.21.B1 | 7-deaza-2'-deoxyxanthosine-containing DNA + H2O |
normal ssDNA, dsDNA and the DNA containing a G/T mismatch are completely resistant to the cleavage reaction. The lengths of the products indicate that PfuEndoQ cleaves DNA on the 5'-side of the lesions |
Pyrococcus furiosus |
? |
- |
? |
3.1.21.B1 | 7-deaza-2'-deoxyxanthosine-containing DNA + H2O |
the enzyme cleaves a ligatable nick (5'-phosphate and 3'-hydroxyl termini) on substrates after the cleavage |
Thermococcus kodakarensis |
? |
- |
? |
3.1.21.B1 | apurinic/apyrimidinic site-containing DNA + H2O |
normal ssDNA, dsDNA and the DNA containing a G/T mismatch are completely resistant to the cleavage reaction. The lengths of the products indicate that PfuEndoQ cleaves DNA on the 5'-side of the lesions |
Pyrococcus furiosus |
? |
- |
? |
3.1.21.B1 | apurinic/apyrimidinic site-containing DNA + H2O |
the enzyme cleaves a ligatable nick (5'-phosphate and 3'-hydroxyl termini) on substrates after the cleavage |
Thermococcus kodakarensis |
? |
- |
? |
3.1.21.B1 | deoxyinosine-containing deoxyoligonucleotide + H2O |
the enzyme is involved in damaged DNA repair |
Pyrococcus furiosus |
? |
- |
? |
3.1.21.B1 | deoxyinosine-containing deoxyoligonucleotide + H2O |
endonucleolytic cleavage of the phosphodiester bond 5' from deoxyinosine |
Pyrococcus furiosus |
? |
- |
? |
3.1.21.B1 | deoxyinosine-containing DNA + H2O |
the enzyme cleaves the phosphodiester bond 5' from deoxyinosine. The enzyme is an endonuclease that functions in a repair process for damaged bases in archaeal cells |
Pyrococcus furiosus |
? |
- |
? |
3.1.21.B1 | deoxyinosine-containing DNA + H2O |
the enzyme cleaves the phosphodiester bond 5' from deoxyinosine. The enzyme is an endonuclease that functions in a repair process for damaged bases in archaeal cells |
Thermococcus kodakarensis |
? |
- |
? |
3.1.21.B1 | deoxyinosine-containing DNA + H2O |
the enzyme cleaves the phosphodiester bond 5' from deoxyinosine |
Thermococcus kodakarensis |
? |
- |
? |
3.1.21.B1 | deoxyinosine-containing DNA + H2O |
the enzyme cleaves the phosphodiester bond 5' from deoxyinosine. The normal ssDNA, dsDNA and the DNA containing a G/T mismatch are completely resistant to the cleavage reaction. The lengths of the products indicate that PfuEndoQ cleaves DNA on the 5'-side of the lesions |
Pyrococcus furiosus |
? |
- |
? |