EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
Homo sapiens |
adenosine 3',5'-diphosphate + [heparan sulfate]-glucosamine 3-sulfate |
- |
? |
2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
does not make active heparan sulfate, transfers sulfate to GlcA2S-GlcNS and IdoA2S-GlcNS |
Homo sapiens |
adenosine 3',5'-diphosphate + [heparan sulfate]-glucosamine 3-sulfate |
- |
? |
2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
Homo sapiens |
adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate |
- |
? |
2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
Danio rerio |
adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate |
- |
? |
2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
Drosophila melanogaster |
adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate |
i.e. HSgD+, 3-O-sulfated motifs that bind the gD envelope protein of Herpes simplex virus 1 mediating the viral cellular entry, overview |
? |
2.8.2.29 | 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine |
- |
Drosophila melanogaster |
adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate |
i.e. HSgD+, 3-O-sulfated motifs that bind the gD envelope protein of Herpes simplex virus 1 |
? |
2.8.2.29 | more |
a gD-type-3-OST isozyme is essential for a conserved neurogenic signaling pathway regulated by Notch |
Drosophila melanogaster |
? |
- |
? |
2.8.2.29 | more |
heparan sulfate chains contain sulfated domains termed the HS fine structure, which gives HS specific binding affinities for extracellular ligands, heparan sulfate 3-O-sulfotransferases catalyze the transfer of sulfate groups to the 3-O position of glucosamine residues of heparan sulfate, a rare, but essential heparan sulfate chain modification required for HS fine structure |
Danio rerio |
? |
- |
? |
2.8.2.29 | more |
modification of heparan sulfate and the ability of 3-OST-2 to generate receptors for both wild-types and some mutant forms of HSV-1, spreading of receptors mediating cell-to-cell fusion |
Homo sapiens |
? |
- |
? |
2.8.2.29 | more |
HSV-1 glycoprotein gD, both the wild-type and the mutant Rid1 form, can interact with [heparan sulfate]-glucosamine 3-sulfate generated by HS 3-OST-2, overview |
Homo sapiens |
? |
- |
? |