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Results 1 - 4 of 4
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.7.7.81CTP + 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid CMP-pseudaminic acid biosynthesis. Helicobacter pylori, heavily modifies its flagellin with pseudaminic acid, a modification that influences pathogenesis through bacterial adhesion, invasion, and immune evasion Helicobacter pylori diphosphate + CMP-5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid - ?
Display the reaction diagram Show all sequences 2.7.7.81CTP + 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid when all six CMP-pseudaminic acid biosynthetic enzymes (PseB, PseC, PseH, PseG, PseI, PseF) are combined in a reaction with UDP-N-acetylglucosamine, synthesis of VII is successful CMP-pseudaminic acid. Combining the first five enzymes (PseB, PseC, PseH, PseG, PseI) in a one-pot reaction results in 100% conversion of UDP-N-acetylglucosamine to pseudaminic acid after 20 h Helicobacter pylori diphosphate + CMP-5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid - ?
Display the reaction diagram Show all sequences 2.7.7.81CTP + 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid - Helicobacter pylori diphosphate + CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid - ?
Display the reaction diagram Show all sequences 2.7.7.81CTP + 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid - Helicobacter pylori P12 diphosphate + CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid - ?
Results 1 - 4 of 4