EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.7.8 | 2',3'-cyclic RNAn + phosphate |
- |
Staphylococcus aureus |
RNA(n-1) + a nucleotide diphosphate |
- |
? |
2.7.7.8 | 24-nucleotide RNA molecule + ADP |
when both ADP and phosphate are present at the reaction mixture, the direction of activity, either polyadenylation or degradation, is dependent on their relative concentrations |
Homo sapiens |
25-nucleotide RNA molecule + phosphate |
- |
r |
2.7.7.8 | 24-nucleotide RNA molecule + phosphate |
when both ADP and phosphate are present at the reaction mixture, the direction of activity, either polyadenylation or degradation, is dependent on their relative concentrations |
Homo sapiens |
23-nucleotide RNA molecule + nucleoside diphosphate |
- |
r |
2.7.7.8 | 3'-phosphorylated RNA(n) + phosphate |
- |
Staphylococcus aureus |
RNA(n-1) + a nucleotide diphosphate |
enzyme inefficiently degrades 3'-phosphorylated RNA |
? |
2.7.7.8 | ADP + globin mRNAn |
- |
Escherichia coli |
globin mRNAn+1 + phosphate |
- |
? |
2.7.7.8 | microR-221 RNAn+1 + phosphate |
recombinantly expressed microRNAs miR-let7a, miR-106b, miR-25, miR-221, miR-222, and miR-184 as substrates, the recombinant enzyme selectively and preferentially degrades microRNA-221 in human melanoma cells |
Homo sapiens |
microR-221 RNAn + ADP |
- |
r |
2.7.7.8 | microRNAn+1 + phosphate |
recombinantly expressed microRNAs miR-let7a, miR-106b, miR-25, miR-221, miR-222, and miR-184 |
Homo sapiens |
microRNAn + ADP |
- |
r |
2.7.7.8 | more |
enzyme is involved in tuning the expression of virulence genes and bacterial fitness during infection |
Salmonella enterica |
? |
- |
? |
2.7.7.8 | more |
enzyme may play a role in excluding oxidized forms of RNA from the translation mechanism |
Homo sapiens |
? |
- |
? |
2.7.7.8 | more |
suppression of Rho-dependent transcription termination within the enzyme gene and its restoration by enzyme protein is an autogenous regulation circuit that modulates enzyme gene expression during cold acclimation |
Escherichia coli |
? |
- |
? |