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Results 1 - 2 of 2

EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.7.7.66	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-[acyl-carrier protein]	-	Klebsiella pneumoniae	malonate decarboxylase holo-[acyl-carrier protein] + diphosphate	-	?
2.7.7.66	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-[acyl-carrier protein]	MdcG forms a strong complex with the 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA prosthetic group precursor. This complex is called MdcGi. Upon incubation of MdcGi with apo acyl carrier protein, holo acyl carrier protein is synthesized by forming the phosphodiester bond between the 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and Ser25 of the protein. In absence of the prosthetic group precursor, MdcG catalyzes at a low rate the adenylylation of apo acyl carrier protein using ATP as substrate. The adenylyl ACP thus formed is an unphysiological side product and is not involved in the biosynthesis of holo ACP	Klebsiella pneumoniae	malonate decarboxylase holo-[acyl-carrier protein] + diphosphate	-	?

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Release 2023.1 (January 2023)