Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 306 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48(dT)12 + UTP assay uses poly(A) as an RNA template and oligo(dT)12-18 as the primer. Enzyme is strictly dependent on the presence of primer Hepacivirus C diphosphate + ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.482'-C-methyl-ATP + RNAn - Severe acute respiratory syndrome coronavirus 2 diphosphate + RNAn+1 - ir
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.485-fluorouridine triphosphate + RNAn the enzyme incorporates 5-fluorouridine monophosphate during RNA elongation in place of UMP or CMP using homopolymeric and heteropolymeric templates. Incorporation of 5-fluorouridine monophosphate does not prevent chain elongation, and, in some sequence contexts, it favors misincorporations at downstream positions. 5-Fluorouridine monophosphate is incorporated into the nascent RNA and occupies the new 3'-end of the primer at the active site of the enzyme. 5-Fluorouridine monophosphate establishes a Watson and Crick pair with the corresponding acceptor AMP in the template strand and an additional hydrogen bond with Ser304 of the polymerase. Further interactions, similar to those observed with standard nucleotides, contribute also to stabilize 5-fluorouridine monophosphate in the 3'-terminus of the RNA. When present in the template, 5-fluorouridine monophosphate directs the incorporation of AMP and GMP, with ATP being a more effective substrate than GTP. The misincorporation of GMP is 17fold faster opposite 5-fluorouridine than opposite U in the template. But Incorporated 5-fluorouridine monophosphate is not a chain terminator during RNA elongation Foot-and-mouth disease virus diphosphate + RNAn+1 RNA with incoporated 5-fluorouridine phosphate ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ara-ATP + RNAn - Severe acute respiratory syndrome coronavirus 2 diphosphate + RNAn+1 - ir
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ATP + poly(U) - Zika virus diphosphate + ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ATP + poly(U) - Zika virus MR766 diphosphate + ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ATP + RNAn - Yellow fever virus diphosphate + RNAn+1 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ATP + RNAn - Hepacivirus C diphosphate + RNAn+1 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ATP + RNAn - West Nile virus diphosphate + RNAn+1 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.48ATP + RNAn - Japanese encephalitis virus diphosphate + RNAn+1 - ?
Results 1 - 10 of 306 > >>