EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.11.21 | ATP + 20S proteasome |
phosphorylation by Plk1 enhances the proteolytic activity |
Homo sapiens |
ADP + phosphorylated S20 proteasome |
- |
? |
2.7.11.21 | ATP + 3F3/2 kinase |
the enzyme creates the 3F3/2 kinase phosphoepitope on mitotic kinetichores, depletion of enzyme in M phase cell extract leads to loss of 3F3/2 kinase activity |
Homo sapiens |
ADP + phosphorylated 3F3/2 kinase |
- |
? |
2.7.11.21 | ATP + 3F3/2 kinase |
the enzyme creates the 3F3/2 kinase phosphoepitope on mitotic kinetichores, depletion of enzyme in M phase cell extract leads to loss of 3F3/2 kinase activity |
Xenopus laevis |
ADP + phosphorylated 3F3/2 kinase |
- |
? |
2.7.11.21 | ATP + 3F3/2 kinase |
purified recombinant Plk1 or M phase cell extract, phosphoepitope mapping reveals that the 3F3/2 kinase phosphoepitope overlaps the enzyme consensus phosphorylation seqence, overview |
Homo sapiens |
ADP + phosphorylated 3F3/2 kinase |
- |
? |
2.7.11.21 | ATP + 3F3/2 kinase |
purified recombinant Plk1 or M phase cell extract, phosphoepitope mapping reveals that the 3F3/2 kinase phosphoepitope overlaps the enzyme consensus phosphorylation seqence, overview |
Xenopus laevis |
ADP + phosphorylated 3F3/2 kinase |
- |
? |
2.7.11.21 | ATP + 53BP1 |
53BP1 is phosphorylated by Plk1 in mitosis |
Homo sapiens |
ADP + phosphorylated 53BP1 |
- |
? |
2.7.11.21 | ATP + 53BP1 |
53BP1 is phosphorylated by Plk1 in its C-terminal domain at Ser1618 in the UDR domain |
Homo sapiens |
ADP + phosphorylated 53BP1 |
- |
? |
2.7.11.21 | ATP + 5FAM-RALMEASFADQAR-NH2 |
substrate peptide, based on human Cdc25C, used in biochemical activity assay |
Danio rerio |
ADP + phosphorylated 5FAM-RALMEASFADQAR-NH2 |
- |
? |
2.7.11.21 | ATP + 85kDa microtubule-associated protein |
- |
Drosophila melanogaster |
ADP + phosphorylated 85kDa microtubule-associated protein |
- |
? |
2.7.11.21 | ATP + 85kDa microtubule-associated protein |
protein is released from microtubules after phosphorylation |
Drosophila melanogaster |
ADP + phosphorylated 85kDa microtubule-associated protein |
- |
? |