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EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo	Shewanella japonica	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo	Shewanella oneidensis	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo	Shewanella japonica	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N, the D-manno-configuration of the monosaccharide is determined by Mosher ester method, absolute configuration is 4R,5R,6R,7R, NMR spectrometry, overview	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo, direct conversion of Kdo to Kdo8N prior to its incorporation into the Kdo8N-lipid A domain of lipopolysaccharide by a metal-dependent oxidase KdnB, EC 1.1.3.48, followed by a glutamate-dependent aminotransferase KdnA, EC 2.3.1.09, the electron acceptor is molecular oxygen	Shewanella oneidensis	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo	Shewanella japonica KMM 3772	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo	Shewanella japonica KMM 3772	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N, the D-manno-configuration of the monosaccharide is determined by Mosher ester method, absolute configuration is 4R,5R,6R,7R, NMR spectrometry, overview	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo	Shewanella oneidensis MR-1 / ATCC 700550	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N	?
2.6.1.109	8-dehydro-3-deoxy-D-manno-octulosonic acid + L-glutamate	i.e. Kdo, direct conversion of Kdo to Kdo8N prior to its incorporation into the Kdo8N-lipid A domain of lipopolysaccharide by a metal-dependent oxidase KdnB, EC 1.1.3.48, followed by a glutamate-dependent aminotransferase KdnA, EC 2.3.1.09, the electron acceptor is molecular oxygen	Shewanella oneidensis MR-1 / ATCC 700550	8-amino-3,8-dideoxy-D-manno-octulosonic acid + 2-oxoglutarate	i.e. Kdo8N	?
2.6.1.109	more	the reaction catalyzed by KdnB, EC 1.1.3.48, is thermodynamically unfavorable and requires the second reaction catalyzed by KdnA to drive product formation, both enzymes are required for product formation. Production of H2O2 when Mn-KdnB and PLP-KdnA are incubated with Kdo and L-Glu	Shewanella oneidensis	?	-	?
2.6.1.109	more	the reaction catalyzed by KdnB, EC 1.1.3.48, is thermodynamically unfavorable and requires the second reaction catalyzed by KdnA to drive product formation, both enzymes are required for product formation. Production of H2O2 when Mn-KdnB and PLP-KdnA are incubated with Kdo and L-Glu	Shewanella oneidensis MR-1 / ATCC 700550	?	-	?

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Release 2023.1 (January 2023)