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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36diethylamino(benzylidine-amino)guanidine + NAD+ DEABAG Vibrio cholerae serotype O1 ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36eEF2 + NAD+ i.e. eukaryotic elongation factor 2, contains a post-translationally modified histidine residue, known as diphthamide, which is the specific ADP-ribosylation target of Pseudomonas aeruginosa exotoxin A Pseudomonas aeruginosa eEF2 N-(ADP-D-ribosyl)diphthamide + NADH + H+ - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36eEF2 + NAD+ i.e. eukaryotic elongation factor 2 with a diphthamide-containing loop comprising residues Leu693-Gly703, ADP-ribosylation at His699, site determination by mass spectrometry and mutational analysis, overview Pseudomonas aeruginosa eEF2 N-(ADP-D-ribosyl)diphthamide + NADH + H+ - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36more NAD+-dependent ADP-ribosyltransfer (ADPRT) including NAD+-glycohydrolysis (GH) activity, deadly virulent due to covalent modification and thus inactivation of proteins that are essential for the host Pseudomonas aeruginosa ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36more no ADP-ribosyl transfer by mutants R551H and R551C despite of occurring NAD+-binding and hydrolysis Pseudomonas aeruginosa ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36more cholera toxin activates mouse bone marrow mast cells to release interleukin-4 via activation of nucleotide oligomerisation domain 1 and toll-like receptor-4, and initiation of antigen-specific T-helper 2 response Vibrio cholerae serotype O1 ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36NAD+ + diphthamide-[Escherichia coli elongation factor Tu] - Entamoeba histolytica nicotinamide + N-(ADP-D-ribosyl)diphthamide-[Escherichia coli elongation factor Tu] - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36NAD+ + diphthamide-[translation elongation factor 2] - Aeromonas hydrophila nicotinamide + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36NAD+ + diphthamide-[translation elongation factor 2] - Pseudomonas aeruginosa nicotinamide + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.36NAD+ + diphthamide-[translation elongation factor 2] - Vibrio cholerae nicotinamide + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] - ?
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