EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.287 | more |
the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf |
Mycobacterium tuberculosis |
? |
- |
? |
2.4.1.287 | more |
the enzyme harbors dual beta-(1->4) and beta-(1->5) galactofuranose transferase activities. The enzyme cannot catalyze subsequent galactan chain extension. Gal-Gal-Gal-Rha-GlcNAc-P-P-decaprenol is not a substrate |
Mycolicibacterium smegmatis |
? |
- |
? |
2.4.1.287 | more |
enzyme requires a substrate bearing the disaccharide L-Rha-alpha-(1,3)-D-GlcNAc. Phosphonophosphate analogues serve as effective substrates, being processed to lipid-linked oligosaccharides |
Mycobacterium tuberculosis |
? |
- |
? |
2.4.1.287 | more |
the bifunctional enzyme is responsible for the initial synthesis of C50-P-P-GlcNAc-Rha-Galf, followed by immediate conversion to C50-P-P-GlcNAc-Rha-Galf-Galf |
Mycobacterium tuberculosis H37Rv |
? |
- |
? |
2.4.1.287 | more |
enzyme requires a substrate bearing the disaccharide L-Rha-alpha-(1,3)-D-GlcNAc. Phosphonophosphate analogues serve as effective substrates, being processed to lipid-linked oligosaccharides |
Mycobacterium tuberculosis ATCC 25618 |
? |
- |
? |
2.4.1.287 | UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol |
synthetic substrate surrogate. Substitution of the farnesol group to isoprenol reduces activity by about 75% |
Mycobacterium tuberculosis |
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol |
- |
? |
2.4.1.287 | UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol |
synthetic substrate surrogate. Substitution of the farnesol group to isoprenol reduces activity by about 75% |
Mycobacterium tuberculosis ATCC 25618 |
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-(2Z,6Z)-farnesol |
- |
? |
2.4.1.287 | UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol |
- |
Mycobacterium tuberculosis |
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol |
- |
? |
2.4.1.287 | UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol |
- |
Mycobacterium tuberculosis ATCC 25618 |
UDP + beta-D-galactofuranosyl-(1-4)-alpha-L-rhamnopyranosyl-(1-3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octacis-decaprenol |
- |
? |
2.4.1.287 | UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol |
- |
Mycolicibacterium smegmatis |
UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol |
- |
? |