EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   2.4.1.222 | epidermal growth factor-like sequence repeats-O-fucose + UDP-GlcNAc |
Drosophila Fringe, Lunic Fringe, Manic Fringe |
Drosophila melanogaster |
? |
- |
? |
| 2.4.1.222 | epidermal growth factor-like sequence repeats-O-fucose + UDP-GlcNAc |
Drosophila Fringe, Lunic Fringe, Manic Fringe |
Mammalia |
? |
- |
? |
| 2.4.1.222 | factor VII EGF repeat + UDP-D-GlcNAc |
Manic fringe modifies O-fucose on mouse Notch1 at extracellular epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region expressed in Lec1 cells |
Drosophila melanogaster |
beta-D-glucosaminyl-factor VII EGF repeat + UDP |
- |
? |
| 2.4.1.222 | L-fucose + GlcNAc |
- |
Drosophila melanogaster |
GlcNAc-beta-1,3-fucitol |
- |
? |
| 2.4.1.222 | more |
further substrate: recombinant epidermal growth factor repeat from the serum protein factor VII modified with O-linked fucose |
Drosophila melanogaster |
? |
- |
? |
| 2.4.1.222 | more |
further substrate: recombinant epidermal growth factor repeat from the serum protein factor VII modified with O-linked fucose |
Mammalia |
? |
- |
? |
| 2.4.1.222 | more |
no substrates: p-nitrophenyl-galactose, p-nitrophenyl-glucose |
Drosophila melanogaster |
? |
- |
? |
| 2.4.1.222 | more |
no substrates: p-nitrophenyl-galactose, p-nitrophenyl-glucose |
Mammalia |
? |
- |
? |
| 2.4.1.222 | more |
ligand-receptor interactions and role of fringe glycosylation, regulation of signaling, overview, Fringe proteins do not influence the surface expression of Notch1 |
Rattus norvegicus |
? |
- |
? |
| 2.4.1.222 | more |
activity on different factor VII EGF repeat containing protein fragments, overview |
Drosophila melanogaster |
? |
- |
? |
