EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.B39 | 8 malonyl-CoA + 4 NADPH + 16 H+ |
- |
Penicillium brefeldianum |
8 CoA + (2E,4E,10E)-15-hydroxyhexadeca-2,4,10-trienoic acid + 8 CO2 + 4 NADP+ + 6 H2O |
main product in presence of thiohydrolase Bref-TH |
? |
2.3.1.B39 | 8 malonyl-CoA + 4 NADPH + 16 H+ |
- |
Penicillium brefeldianum ATCC 58665 |
8 CoA + (2E,4E,10E)-15-hydroxyhexadeca-2,4,10-trienoic acid + 8 CO2 + 4 NADP+ + 6 H2O |
main product in presence of thiohydrolase Bref-TH |
? |
2.3.1.B39 | 9 malonyl-CoA + 5 NADPH + 19 H+ |
- |
Penicillium brefeldianum |
9 CoA + (4E,6Z,12E)-17-hydroxyoctadeca-4,6,12-trienoic acid + 9 CO2 + 5 NADP+ + 7 H2O |
main product in absence of thiohydrolase Bref-TH |
? |
2.3.1.B39 | 9 malonyl-CoA + 5 NADPH + 19 H+ |
- |
Penicillium brefeldianum ATCC 58665 |
9 CoA + (4E,6Z,12E)-17-hydroxyoctadeca-4,6,12-trienoic acid + 9 CO2 + 5 NADP+ + 7 H2O |
main product in absence of thiohydrolase Bref-TH |
? |
2.3.1.B39 | more |
enzyme shows an NADPH-dependent reductive tailoring specificity that leads to the synthesis of four different oktaketide products with varying degrees of reduction. Bref-PKS is a nonaketide synthase in the absence of an associated thiohydrolase Bref-TH |
Penicillium brefeldianum |
? |
- |
? |
2.3.1.B39 | more |
enzyme shows an NADPH-dependent reductive tailoring specificity that leads to the synthesis of four different oktaketide products with varying degrees of reduction. Bref-PKS is a nonaketide synthase in the absence of an associated thiohydrolase Bref-TH |
Penicillium brefeldianum ATCC 58665 |
? |
- |
? |