EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.1.225 | more |
in the absence of cellular factors, palmitoyl-CoA is capable of spontaneously S-acylating cysteinyl thiols, overview |
Drosophila melanogaster |
? |
- |
? |
2.3.1.225 | more |
in the absence of cellular factors, palmitoyl-CoA is capable of spontaneously S-acylating cysteinyl thiols, overview. Effects of APT1 on palmitate turnover on Gsalpha are not due to effects on the rate of turnover of palmitoyl-CoA |
Rattus norvegicus |
? |
- |
? |
2.3.1.225 | more |
in the absence of cellular factors, palmitoyl-CoA is capable of spontaneously S-acylating cysteinyl thiols, overview. Effects of APT1 on palmitate turnover on Gsalpha are not due to effects on the rate of turnover of palmitoyl-CoA |
Saccharomyces cerevisiae |
? |
- |
? |
2.3.1.225 | more |
in the absence of cellular factors, palmitoyl-CoA is capable of spontaneously S-acylating cysteinyl thiols, overview. G protein alpha subunit GsR is first acylated at Cys-3, then the palmitate is transferred to the amino group of Gly-2 through a cyclic intermediate as is postulated for hedgehog |
Homo sapiens |
? |
- |
? |
2.3.1.225 | more |
APT1 has acyl-CoA hydrolase activity |
Rattus norvegicus |
? |
- |
? |
2.3.1.225 | more |
APT1 has acyl-CoA hydrolase activity |
Saccharomyces cerevisiae |
? |
- |
? |
2.3.1.225 | more |
complexity of HIP14's substrate specificity, in vitro, HIP14 has PAT activity for the N-terminal fragment of htt(1-548), SNAP-25, PSD-95, GAD65, and synaptotagmin I but not for synaptotagmin VII and paralemmin |
Homo sapiens |
? |
- |
? |
2.3.1.225 | more |
DHHC2 has a broad protein substrate specificity. DHHC2 transfers fatty acids from all acyl-CoA chain lengths tested, consistent with it having a broad specificity for long chain acyl-CoAs, and acyl-CoAs of 14 carbons and longer inhibit palmitoyl-CoA labeling of both substrate and enzyme. The acyl-CoA chain length specificity of DHHC enzyme autoacylation parallels substrate specificity, overview |
Homo sapiens |
? |
- |
? |
2.3.1.225 | more |
DHHC3 has a broad protein substrate specificity, but only myristoyl-, palmitoyl-, and palmioleoyl-CoA are effective, and longer acyl-CoAs compete less well. The acyl-CoA chain length specificity of DHHC enzyme autoacylation parallels substrate specificity, overview |
Mus musculus |
? |
- |
? |
2.3.1.225 | more |
G-protein substrate specificity of PAT activity, overview. Mutation of the prenylated cysteine residue to serine, C68S, in the gamma2 subunit yields a nonprenylated gamma that heterodimerizes with the beta1 subunit. The mutant betagammaC68S binds to myristoylated rGialpha1, forming a heterotrimer that is acylated in vitro with efficiency similar to that of the wild-type heterotrimer |
Rattus norvegicus |
? |
- |
? |