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EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.3.1.216	5 malonyl-CoA	-	Aloe arborescens	5 CoA + 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O	-	?
2.3.1.216	more	recombinant pentaketide chromone synthasedoes not produce chalcone from 4-coumaroyl-CoA, but instead efficiently accepts malonyl-CoA as a sole substrate to carry out iterative condensations of five molecules of malonyl-CoA, producing a pentaketide, 5,7-dihydroxy-2-methylchromone. Recombinant pentaketide chromone synthaseaccepts acetyl-CoA, resulting from decarboxylation of malonyl-CoA, as a starter substrate	Aloe arborescens	?	-	?

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Release 2023.1 (January 2023)