EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.354 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 |
overall reaction |
Mus musculus |
3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 |
- |
? |
2.1.1.354 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 |
overall reaction |
Saccharomyces cerevisiae |
3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 |
- |
? |
2.1.1.354 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 |
overall reaction |
Caenorhabditis elegans |
3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 |
- |
? |
2.1.1.354 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 |
overall reaction |
Oryza sativa |
3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 |
- |
? |
2.1.1.354 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 |
overall reaction |
Homo sapiens |
3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 |
- |
? |
2.1.1.354 | 3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 |
overall reaction |
Saccharomyces cerevisiae BY4741 |
3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4 |
- |
? |
2.1.1.354 | more |
Set1/CXXC finger protein 1 complex transfers tritiated methyl groups onto both purified core histones and recombinant histone H3, fails to catalyze methylation of histone H4, specificity for histone H3-Lys4 methylation |
Homo sapiens |
? |
- |
? |
2.1.1.354 | more |
SET1 mRNA is associated with a SET1C sub-complex |
Saccharomyces cerevisiae |
? |
- |
? |
2.1.1.354 | more |
CXXC finger protein 1 is a component of the Setd1A and Setd1B histone H3K4 methyltransferase complex |
Homo sapiens |
? |
- |
? |
2.1.1.354 | more |
fusing the enzyme to RNA polymerase II results in extended histone H3 lysine 4 methylation throughout the gene |
Saccharomyces cerevisiae |
? |
- |
? |