Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 16 > >>
download as CSV
download all results as CSV
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more isoform HemK methylates peptide release factors RF1 and RF2 in vitro within the tryptic fragment containing the conserved GGQ motif, and hemK is required for the methylation within the same fragment of, at least, RF1 in vivo Escherichia coli ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more PrmC methylates chlamydia peptide release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more no evidence for a DNA adenine-methyltransferase activity Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more PrmC methylates release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more the catalytic methyl transfer by methyltransferase HemK is an energy-favored process with an activation barrier of 15.7 kcal/mol and an exothermicity of 12.0 kcal/mol, while the coenzyme-modified HemK is unable to catalyze the methyl transfer because of a substantial barrier of 20.6 kcal/mol and instability of the product intermediate. Therefore the nitrogen analogue of the SAM coenzyme should be a practicable inhibitor for the catalytic methyl transfer by HemK. The protein environment, especially the residues Asn197 and Pro198 in the active site, plays a pivotal role in stabilizing the transition state and regulating the positioning of reactive groups Thermotoga maritima ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more the catalytic methyl transfer by methyltransferase HemK is an energy-favored process with an activation barrier of 15.7 kcal/mol and an exothermicity of 12.0 kcal/mol, while the coenzyme-modified HemK is unable to catalyze the methyl transfer because of a substantial barrier of 20.6 kcal/mol and instability of the product intermediate. Therefore the nitrogen analogue of the SAM coenzyme should be a practicable inhibitor for the catalytic methyl transfer by HemK. The protein environment, especially the residues Asn197 and Pro198 in the active site, plays a pivotal role in stabilizing the transition state and regulating the positioning of reactive groups Thermotoga maritima DSM 3109 ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more PrmC methylates chlamydia peptide release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ATCC VR-902B ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297more PrmC methylates release factors within the tryptic fragment containing the universally conserved sequence motif Gly-Gly-Gln Chlamydia trachomatis ATCC VR-902B ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297S-adenosyl-L-methionine + [peptide chain release factor 1 or 2]-L-glutamine - Thermotoga maritima S-adenosyl-L-homocysteine + [peptide chain release factor 1 or 2]-N5-methyl-L-glutamine - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.297S-adenosyl-L-methionine + [peptide chain release factor 1 or 2]-L-glutamine - Thermotoga maritima DSM 3109 S-adenosyl-L-homocysteine + [peptide chain release factor 1 or 2]-N5-methyl-L-glutamine - ?
Results 1 - 10 of 16 > >>
download as CSV
download all results as CSV