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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
2.1.1.258
cobalamin + 5-methyltetrahydrofolate
reaction is pH dependent with the best pH of around 5.0
Clostridioides difficile
methylcobalamin + tetrahydrofolate
-
?
2.1.1.258
cobalamin + 5-methyltetrahydrofolate
reaction is pH dependent with the best pH of around 5.0
Clostridioides difficile 630
methylcobalamin + tetrahydrofolate
-
?
2.1.1.258
hydroxocobalamin + 5-methyltetrahydrofolate
-
Moorella thermoacetica
methylcobalamin + tetrahydrofolate
-
r
2.1.1.258
hydroxycobalamin + 5-methyltetrahydrofolate
-
Clostridioides difficile
methylcobalamin + tetrahydrofolate
-
?
2.1.1.258
hydroxycobalamin + 5-methyltetrahydrofolate
-
Clostridioides difficile 630
methylcobalamin + tetrahydrofolate
-
?
2.1.1.258
methylcobalamin + tetrahydrofolate
-
Moorella thermoacetica
?
-
?
2.1.1.258
methylcobalamin + tetrahydrofolate
-
Moorella thermoacetica
hydroxocobalamin + 5-methyltetrahydrofolate
-
?
2.1.1.258
methylcobalamin + tetrahydrofolate
-
Moorella thermoacetica
hydroxocobalamin + 5-methyltetrahydrofolate
-
r
2.1.1.258
more
only the protonated enzyme form is active
Moorella thermoacetica
?
-
?
2.1.1.258
[Co(I) corrinoid Fe-S protein] + 5-methyltetrahydrofolate
-
Moorella thermoacetica
[methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate
-
?
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