EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  1.5.3.4 | 6-(methylamino)-2-oxohexanoic acid + H2O + O2 |
- |
Rattus norvegicus |
6-amino-2-oxohexanoic acid + formaldehyde + H2O2 |
- |
? |
| 1.5.3.4 | 6-(methylamino)-2-oxohexanoic acid + H2O + O2 |
15% of the activity with N6-methyl-L-lysine |
Rattus norvegicus |
6-amino-2-oxohexanoic acid + formaldehyde + H2O2 |
- |
? |
| 1.5.3.4 | 6-(methylamino)-2-oxohexanoic acid + H2O + O2 |
free alpha-amino group is not required for susceptibility |
Rattus norvegicus |
6-amino-2-oxohexanoic acid + formaldehyde + H2O2 |
- |
? |
| 1.5.3.4 | epsilon-N-methyl groups in protein-bound methyllysine residues + O2 + H2O |
methylation of lysyl residues is catalyzed by S-adenosylmethionine:protein (lysine) N-methyltransferase |
Rattus norvegicus |
demethylated lysine residues + formaldehyde + H2O2 |
- |
ir |
| 1.5.3.4 | epsilon-N-methyl groups in protein-bound methyllysine residues + O2 + H2O |
protein: e.g. histones |
Rattus norvegicus |
demethylated lysine residues + formaldehyde + H2O2 |
- |
ir |
| 1.5.3.4 | more |
not: delta-N-monomethyl-L-ornithine |
Rattus norvegicus |
? |
- |
? |
| 1.5.3.4 | more |
demethylation involves an electron transport system: FAD is the physiological electron acceptor, phenazine methosulfate as artificial and more efficient electron acceptor than FAD, final electron acceptor is oxygen or 2,6-dichlorophenolindophenol |
Rattus norvegicus |
? |
- |
? |
| 1.5.3.4 | more |
not: several acyl derivatives, alpha-N-methyl-L-lysine |
Rattus norvegicus |
? |
- |
? |
| 1.5.3.4 | more |
activity restricted to epsilon-N-alkyllysine derivatives |
Rattus norvegicus |
? |
- |
? |
| 1.5.3.4 | N6,N6-dimethyl-L-lysine + O2 + H2O |
- |
Rattus norvegicus |
L-lysine + formaldehyde + H2O2 |
- |
? |
