EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + glyoxylate + NADPH + H+ |
the enzyme prefers the alpha-oxo acid substrate pyruvate but also exhibits limited turnover with oxaloacetate and glyoxylate |
Staphylococcus aureus |
? + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + glyoxylate + NADPH + H+ |
the enzyme prefers the alpha-oxo acid substrate pyruvate but also exhibits limited turnover with oxaloacetate and glyoxylate |
Staphylococcus aureus ATCC 700699 |
? + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + oxaloacetate + NADPH + H+ |
the enzyme prefers the alpha-oxo acid substrate pyruvate but also exhibits limited turnover with oxaloacetate and glyoxylate |
Staphylococcus aureus |
? + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + oxaloacetate + NADPH + H+ |
the enzyme prefers the alpha-oxo acid substrate pyruvate but also exhibits limited turnover with oxaloacetate and glyoxylate |
Staphylococcus aureus ATCC 700699 |
? + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ |
- |
Staphylococcus aureus |
staphylopine + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ |
the enzyme catalyses the last reaction in the biosynthesis of the metallophore staphylopine, which is involved in the acquisition of nickel, copper, and cobalt |
Staphylococcus aureus |
staphylopine + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ |
the enzyme catalyses the last reaction in the biosynthesis of the metallophore staphylopine. The metallophore play an important role in metal acquisition of zinc, cobalt, nickel, and iron and is also associated with the pathogenesis of several disease states |
Staphylococcus aureus |
staphylopine + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ |
the enzyme prefers the alpha-oxo acid substrate pyruvate but also exhibits limited turnover with oxaloacetate and glyoxylate |
Staphylococcus aureus |
staphylopine + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ |
the enzyme catalyses the last reaction in the biosynthesis of the metallophore staphylopine. The metallophore play an important role in metal acquisition of zinc, cobalt, nickel, and iron and is also associated with the pathogenesis of several disease states |
Staphylococcus aureus ATCC 700699 |
staphylopine + NADP+ + H2O |
- |
? |
1.5.1.52 | (2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ |
the enzyme prefers the alpha-oxo acid substrate pyruvate but also exhibits limited turnover with oxaloacetate and glyoxylate |
Staphylococcus aureus ATCC 700699 |
staphylopine + NADP+ + H2O |
- |
? |