EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  1.5.1.46 | (8beta,10beta)-6-amino-8-methyl-6,7-didehydroergolin-6-ium + NADPH + H+ |
- |
Aspergillus fumigatus |
festuclavine + NADP+ |
- |
? |
| 1.5.1.46 | 6,8-dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+ |
- |
Aspergillus fumigatus |
agroclavine + NADP+ |
- |
? |
| 1.5.1.46 | chanoclavine-I aldehyde + GSH + NADPH + H+ |
the reaction occurs only in the presence of reduced glutathione |
Claviceps purpurea |
agroclavine + GSSG + NADP+ |
- |
? |
| 1.5.1.46 | chanoclavine-I aldehyde + NADH + H+ |
54% conversion compared to NADPH, in the presence of reduced glutathione |
Claviceps purpurea |
agroclavine + NAD+ |
- |
? |
| 1.5.1.46 | chanoclavine-I aldehyde + NADH + H+ |
the reaction occurs only in the presence of reduced glutathione (conversion rate of 54%) |
Claviceps purpurea |
agroclavine + NAD+ |
- |
? |
| 1.5.1.46 | chanoclavine-I aldehyde + NADPH + H+ |
the reaction occurs only in the presence of reduced glutathione or beta-mercaptoethanol or dithiothreitol |
Claviceps purpurea |
agroclavine + NADP+ |
- |
? |
| 1.5.1.46 | chanoclavine-I aldehyde + NADPH + H+ |
the reaction occurs only in the presence of the thiolation agents reduced glutathione (conversion rate of 59%) or 2-mercaptoethanol (conversion rate of 99%) and dithiothreitol (conversion rate of 67%). No product formation is detected in the incubation mixture with L-ascorbic acid instead of GSH |
Claviceps purpurea |
agroclavine + NADP+ |
- |
? |
| 1.5.1.46 | chanoclavine-I aldehyde + NADPH + H+ |
- |
Claviceps purpurea |
festuclavine + pyroclavine + NADP+ |
- |
? |
