EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.2.1.99 | 2-furaldehyde + NAD+ + H2O |
22% of the activity with 3-hydroxypropionaldehyde |
Klebsiella pneumoniae |
furan-2-carboxylate + NADH + 2 H+ |
- |
? |
1.2.1.99 | 3-hydroxypropionaldehyde + NAD+ + H2O |
- |
Klebsiella pneumoniae |
3-hydroxypropanoate + NADH + 2 H+ |
- |
? |
1.2.1.99 | 3-hydroxypropionaldehyde + NAD+ + H2O |
- |
Escherichia coli |
3-hydroxypropanoate + NADH + 2 H+ |
- |
? |
1.2.1.99 | 3-hydroxypropionaldehyde + NAD+ + H2O |
the enzyme might play a role in putresine and propionate metabolism |
Klebsiella pneumoniae |
3-hydroxypropanoate + NADH + 2 H+ |
- |
? |
1.2.1.99 | 3-hydroxypropionaldehyde + NAD+ + H2O |
activity for the reduction of 3-hydroxypropionate to 3-hydroxypropionaldehyde is only 4% of that for the corresponding oxidation reaction, indicating that this enzyme catalyzes oxidation reactions under most physiological conditions |
Escherichia coli |
3-hydroxypropanoate + NADH + 2 H+ |
- |
r |
1.2.1.99 | 3-hydroxypropionaldehyde + NAD+ + H2O |
3-hydroxypropionaldehyde i.e. 3-HPA, 3-hydroxypropionic acid i.e. 3-HP, PuuC overexpression enhances the glycerol carbon flux towards 3-hydroxypropionaldehyde |
Klebsiella pneumoniae |
3-hydroxypropanoate + NADH + 2 H+ |
- |
? |
1.2.1.99 | 3-hydroxypropionaldehyde + NAD+ + H2O |
- |
Klebsiella pneumoniae DSM 2026 |
3-hydroxypropanoate + NADH + 2 H+ |
- |
? |
1.2.1.99 | 3-hydroxypropionaldehyde + NADP+ + H2O |
activity is decreased by 73% when NAD+ is replaced with NADP+. The reduction of 3-hydroxypropionate to 3-hydroxypropionaldehyde is not catalyzed with NADPH as cofactor |
Escherichia coli |
3-hydroxypropanoate + NADPH + 2 H+ |
- |
ir |
1.2.1.99 | 4-(gamma-L-glutamylamino)butanal + NAD+ + H2O |
- |
Escherichia coli |
4-(gamma-L-glutamylamino)butanoate + NADH + H+ |
- |
? |
1.2.1.99 | acetaldehyde + NAD+ + H2O |
- |
Klebsiella pneumoniae |
acetate + NADH + H+ |
- |
? |