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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.2.1.89
D-glyceraldehyde + NAD+
NAD+ is a very poor cofactor for wild-type
Thermoplasma acidophilum
D-glycerate + NADH + H+
-
?
1.2.1.89
D-glyceraldehyde + NAD+ + H2O
activity of mutants N286E, N286H, N286T. No substrate for wild-type
Escherichia coli
D-glycerate + NADH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
-
Thermoplasma acidophilum
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
the enzyme is involved in downstream portion of the non-phosphorylated EntnerDoudoroff pathway
Thermoplasma acidophilum
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
the enzyme is involved in the non-phosphorylative EntnerDoudoroff pathway
Thermoplasma acidophilum
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
the enzyme is involved in the non-phosphorylative EntnerDoudoroff pathway
Picrophilus torridus
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
also accepts NAD+ under technically relevant conditions, cofactor above 1 mM
Thermoplasma acidophilum
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
completely inactive when NAD+ is substituted for NADP+
Thermoplasma acidophilum
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
completely inactive with NAD+
Thermoplasma acidophilum
D-glycerate + NADPH + H+
-
?
1.2.1.89
D-glyceraldehyde + NADP+ + H2O
completely inactive with NAD+
Picrophilus torridus
D-glycerate + NADPH + H+
-
?
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