EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.14.20.1 | (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(thiophen-2-ylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid + 2-oxoglutarate + O2 |
- |
Streptomyces clavuligerus |
(6R,7R)-3-methyl-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid + succinate + CO2 + H2O |
- |
? |
| 1.14.20.1 | 3-exomethylenecephalosporin C + 2-oxoglutarate + O2 |
8% of the activity with cephalosporin N, recombinant enzyme |
Streptomyces clavuligerus |
deacetylcephalosporin C + succinate + CO2 + H2O |
- |
? |
| 1.14.20.1 | 6-alpha-methylpenicillin N + 2-oxoglutarate + O2 |
- |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
? |
| 1.14.20.1 | 6-alpha-methylpenicillin N + 2-oxoglutarate + O2 |
best substrate in the ring expansion reaction |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
ir |
| 1.14.20.1 | 6-aminopenicillanic acid + 2-oxoglutarate + O2 |
- |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
? |
| 1.14.20.1 | 6-aminopenicillanic acid + 2-oxoglutarate + O2 |
low activity, ring expansion reaction |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
ir |
| 1.14.20.1 | 7-aminodeacetoxycephalosporanic acid + 2-oxoglutarate + O2 |
low activity, hydroxylation reaction |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
ir |
| 1.14.20.1 | acetyl-6-aminopenicillanic acid + 2-oxoglutarate + O2 |
- |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
? |
| 1.14.20.1 | acetyl-6-aminopenicillanic acid + 2-oxoglutarate + O2 |
ring expansion reaction |
Acremonium chrysogenum |
? + succinate + CO2 + H2O |
- |
ir |
| 1.14.20.1 | acetyl-6-aminopenicillanic acid + 2-oxoglutarate + O2 |
- |
Streptomyces clavuligerus |
7-acetylaminodesacetoxycephalosporanic acid + succinate + CO2 + H2O |
- |
? |
