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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(R,S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 - Eschscholzia californica (R,S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(R,S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 both CYP719A2 and CYP719A3 have stylopine synthase activity to catalyze methylenedioxy bridge-formation from cheilanthifoline to stylopine, but not cheilanthifoline synthase activity to convert scoulerine to cheilanthifoline, overview Eschscholzia californica (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(R,S)-scoulerine + [reduced NADPH-hemoprotein reductase] + O2 - Eschscholzia californica (S)-nandinine + [oxidized NADPH-hemoprotein reductase] + H2O - r
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 - Eschscholzia californica (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 - Argemone mexicana (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 NADPH is essential for activity, NADH displays only 0.5% turnover of that of NADPH Eschscholzia californica (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 enzyme is induced 20 h after challenging the cell suspension culture with elicitor Eschscholzia californica (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 stylopine biosynthesis involves the sequential formation of two methylenedioxy bridges, (S)-stylopine is an important intermediate in the biosynthesis of benzophenanthridine alkaloids, such as sanguinarine Eschscholzia californica (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 the enzyme is involved in biosynthesis of stylopine Chelidonium majus (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + 2 H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.19.64(S)-cheilanthifoline + [reduced NADPH-hemoprotein reductase] + O2 high substrate specificity. The only alternative substrate identified is scoulerine, which is converted by stylopine synthase to yield minor amounts of nandinine Chelidonium majus (S)-stylopine + [oxidized NADPH-hemoprotein reductase] + 2 H2O - ?
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