EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.19.56 | 1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FADH2 + 2 bromide + 2 O2 |
- |
Pseudomonas fluorescens |
4,5-dibromo-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FAD + 4 H2O |
- |
? |
1.14.19.56 | 1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FADH2 + 2 bromide + 2 O2 |
- |
Pseudomonas fluorescens ATCC BAA-477 |
4,5-dibromo-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FAD + 4 H2O |
- |
? |
1.14.19.56 | 1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FADH2 + 2 chloride + 2 O2 |
- |
Pseudomonas fluorescens |
4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FAD + 4 H2O |
- |
? |
1.14.19.56 | 1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FADH2 + 2 chloride + 2 O2 |
- |
Pseudomonas fluorescens ATCC BAA-477 |
4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + 2 FAD + 4 H2O |
- |
? |
1.14.19.56 | 1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FADH2 + chloride + O2 |
- |
Pseudomonas fluorescens |
5-chloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FAD + 2 H2O |
- |
? |
1.14.19.56 | 1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FADH2 + chloride + O2 |
- |
Pseudomonas fluorescens ATCC BAA-477 |
5-chloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FAD + 2 H2O |
- |
? |
1.14.19.56 | 5-chloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FADH2 + chloride + O2 |
- |
Pseudomonas fluorescens |
4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FAD + H2O |
- |
? |
1.14.19.56 | 5-chloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FADH2 + chloride + O2 |
- |
Pseudomonas fluorescens ATCC BAA-477 |
4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL peptidyl-carrier protein] + FAD + H2O |
- |
? |
1.14.19.56 | more |
halogenase PltA catalyzes chlorination at both positions of the ring, generating the 5-chloropyrrolyl-S-PltL intermediate and then the 4,5-dichloropyrrolyl-S-PltL product. The regiospecific chlorination occurs at position 5 and then position 4 of the heteroaromatic ring. The mechanism may involve formation of a FAD-4a-OCl intermediate for capture by the electron-rich C4 and C5 of the heteroaromatic pyrrole moiety |
Pseudomonas fluorescens |
? |
- |
? |
1.14.19.56 | more |
halogenase PltA catalyzes chlorination at both positions of the ring, generating the 5-chloropyrrolyl-S-PltL intermediate and then the 4,5-dichloropyrrolyl-S-PltL product. The regiospecific chlorination occurs at position 5 and then position 4 of the heteroaromatic ring. The mechanism may involve formation of a FAD-4a-OCl intermediate for capture by the electron-rich C4 and C5 of the heteroaromatic pyrrole moiety |
Pseudomonas fluorescens ATCC BAA-477 |
? |
- |
? |