EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.19.4 | (2S,3R)-2-aminoicosane-1,3-diol + reduced acceptor + O2 |
- |
Helianthus annuus |
(E)-(2S,3R)-2-aminoicos-8-ene-1,3-diol + (Z)-(2S,3R)-2-aminoicos-8-ene-1,3-diol + acceptor + H2O |
- |
? |
1.14.19.4 | (E)-sphing-4-enine + reduced acceptor + O2 |
- |
Candida albicans |
(2S,3R,4E,8E)-2-aminooctadeca-4,8-diene-1,3-diol + acceptor + H2O |
- |
? |
1.14.19.4 | (E)-sphing-4-enine + reduced acceptor + O2 |
- |
Candida albicans TUA6 |
(2S,3R,4E,8E)-2-aminooctadeca-4,8-diene-1,3-diol + acceptor + H2O |
- |
? |
1.14.19.4 | (R)-9-fluorophytosphinganine + reduced acceptor + O2 |
exclusively produces (Z)-9-fluoro-8-phytosphingenine. This result is explained by an initial attack onto the C8-HR and syn-elimination of two vicinal hydrogen atoms via an anti-conformation of the substrate. An initial attack on the C9-F is excluded and generates no product |
Helianthus annuus |
(Z)-9-fluoro-8-phytosphingenine + acceptor + H2O |
- |
? |
1.14.19.4 | (S)-8-fluorophytosphinganine + reduced acceptor + O2 |
product predominantly transformed to (Z)-8-fluoro-8-phytosphingenine along with only trace amounts of the (E)-8-fluoro-8-phytosphingenine (ratio 95:5). This ratio indicates that the fluorinated substrate strongly favors the anti-configuration at the active center of the desaturase |
Helianthus annuus |
(Z)-8-fluoro-8-phytosphingenine + acceptor + H2O |
- |
? |
1.14.19.4 | (S)-9-fluorophytosphinganine + reduced acceptor + O2 |
produces (E)-9-fluoro-8-phytosphingenine as the sole reaction product. Only the initial attack on the C9-HR in combination with the gauche-conformation of the substrate is productive |
Helianthus annuus |
(E)-9-fluoro-8-phytosphingenine + acceptor + H2O |
- |
? |
1.14.19.4 | 11,14,17-eicosatrienoic acid + reduced acceptor + O2 |
- |
Euglena gracilis |
8,11,14,17-eicosatetraenoic acid + acceptor + H2O |
- |
? |
1.14.19.4 | 11,14,17-eicosatrienoic acid + reduced acceptor + O2 |
20:3n-3, yield 20:4n-3 |
Papio anubis |
? |
- |
? |
1.14.19.4 | 11,14-eicosadienoic acid + reduced acceptor + O2 |
- |
Euglena gracilis |
8,11,14-eicosatrienoic acid + acceptor + H2O |
- |
? |
1.14.19.4 | 11,14-eicosadienoic acid + reduced acceptor + O2 |
20:2n-6, yield 20:3n-6 |
Papio anubis |
? |
- |
? |