EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.47 | 2 L-arginine + 2 reduced flavodoxin + 2 O2 |
- |
Geobacillus kaustophilus |
2 Nomega-hydroxy-L-arginine + 2 oxidized flavodoxin + 2 H2O |
- |
? |
1.14.14.47 | 2 L-arginine + 2 tetrahydrobiopterin + 2 O2 |
- |
Bacillus subtilis |
2 Nomega-hydroxy-L-arginine + 2 oxidized tetrahydrobiopterin + 2 H2O |
- |
? |
1.14.14.47 | 2 L-arginine + 2 tetrahydrobiopterin + 2 O2 |
- |
Bacillus subtilis 168 |
2 Nomega-hydroxy-L-arginine + 2 oxidized tetrahydrobiopterin + 2 H2O |
- |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
- |
Bacillus subtilis |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
- |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
- |
Nocardia sp. |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
- |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
- |
Bacillus subtilis |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
overall reaction |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
- |
Bacillus subtilis |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
flavodoxins YkuN and YkuP as well as protein cisJ may be used as redox partners, enzyme uses different available cellular redox partner to support its NO synthesis |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
- |
Bacillus anthracis |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
flavodoxins YkuN and YkuP as well as protein cisJ may be used as redox partners, enzyme uses different available cellular redox partner to support its NO synthesis |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
- |
Bacillus subtilis |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
overall reaction. Flavodoxins YkuN and YkuP support catalysis as kinetically competent redox partners. When an NADPH-utilizing bacterial flavodoxin reductase is added to reduce YkuP or YkuN, both support nitric oxide synthesis from either L-arginine or N-hydroxyarginine, with YkuN being more efficient |
? |
1.14.14.47 | 2 L-arginine + 3 reduced flavodoxin + 4 O2 |
tetrahydrobiopterin or tetrahydrofolate may act as redox partners |
Sorangium cellulosum |
2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H2O |
overall reaction |
? |