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Results 1 - 9 of 9
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151(+)-valencene + [reduced NADPH-hemoprotein reductase] + O2 enzyme HPO-mediated biohydroxylation of (+)-valencene Hyoscyamus muticus alpha-nootkatol + beta-nootkatol + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151(-)-vetispiradiene + [reduced NADPH-hemoprotein reductase] + O2 - Hyoscyamus muticus solavetivol + [oxidized NADPH-hemoprotein reductase] + H2O solavetivol is also named premnaspirodien-2alpha-ol or (2S,4R,5S,7R)-spirovetiva-1(10),11(12)-dien-2-ol ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.1514-epi-eremophilene + [reduced NADPH-hemoprotein reductase] + O2 - Hyoscyamus muticus 4-epieremophilen-2beta-ol + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.1515-epiaristolochene + 3 [reduced NADPH-hemoprotein reductase] + 3 O2 substrate affinity for 5-epiaristolochene is 2-4times lower than that for valencene or (-)-premnaspirodiene, respectively. HPO catalyzes the conversion of 5-epiaristolochene to four mono-hydroxylated products with 2beta-hydroxy-epiaristolochene comprising greater than 80% of the reaction products, 1beta-hydroxy-epiaristolochene about 5%, 3alpha-hydroxy-epiaristolochene less than 2%, and an unknown mono-hydroxylated product of about 20% Hyoscyamus muticus 2beta-hydroxy-5-epiaristolochene + 1beta-hydroxy-5-epiaristolochene + 3alpha-hydroxy-5-epiaristolochene + 3 [oxidized NADPH-hemoprotein reductase] + 3 H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151cedr-8-ene + [reduced NADPH-hemoprotein reductase] + O2 - Hyoscyamus muticus cedr-8-en-15-ol + [oxidized NADPH-hemoprotein reductase] + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151more HPO also catalyzes the equivalent regio-specific (C-2) hydroxylation of several eremophilane-type (decalin ring system) sesquiterpenes, such as with 5-epi-aristolochene Hyoscyamus muticus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151more the enzyme fails to convert nootkatol to nootkatone Hyoscyamus muticus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151more co-expression of enzyme HPO and cytochrome P450 reductase (CPR) leads to the hydroxylation of externally added (+)-valencene to trans-nootkatol in Pichia pastoris cells Hyoscyamus muticus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.151valencene + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 - Hyoscyamus muticus alpha-nootkatol + beta-nootkatol + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O - ?
Results 1 - 9 of 9
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