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Results 1 - 10 of 23

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EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
1.14.13.181	13-deoxycarminomycin + NADPH + H+ + O2	-	Streptomyces sp.	13-dihydrocarminomycin + NADP+ + H2O	-	?
1.14.13.181	13-deoxycarminomycin + NADPH + H+ + O2	DoxA catalyzes three steps in the daunorubicin/doxorubicin biosynthesis pathway: hydroxylation at C13 of 13-deoxycarminomycin and 13-deoxydaunorubicin, oxidation at C-13 of 13-dihydrocarminomycin and daunorubicinol and the hydroxylation at C-14 of daunorubicin	Streptomyces sp.	13-dihydrocarminomycin + NADP+ + H2O	-	?
1.14.13.181	13-deoxycarminomycin + NADPH + H+ + O2	DoxA catalyzes three steps in the daunorubicin/doxorubicin biosynthesis pathway: hydroxylation at C13 of 13-deoxycarminomycin and 13-deoxydaunorubicin, oxidation at C-13 of 13-dihydrocarminomycin and daunorubicinol and the hydroxylation at C-14 of daunorubicin. It appears that the primary function of DoxA is to catalyze the enzymatic conversion of 13-deoxydaunorubicin to daunorubicin via daunorubicinol	Streptomyces sp.	13-dihydrocarminomycin + NADP+ + H2O	-	?
1.14.13.181	13-deoxydaunorubicin + NADPH + H+ + O2	-	Streptomyces sp.	13-dihydrodaunorubicin + NADP+ + H2O	i.e. daunorubicinol	?
1.14.13.181	13-deoxydaunorubicin + NADPH + H+ + O2	DoxA catalyzes three steps in the daunorubicin/doxorubicin biosynthesis pathway: hydroxylation at C13 of 13-deoxycarminomycin and 13-deoxydaunorubicin, oxidation at C-13 of 13-dihydrocarminomycin and daunorubicinol and the hydroxylation at C-14 of daunorubicin	Streptomyces sp.	13-dihydrodaunorubicin + NADP+ + H2O	-	?
1.14.13.181	13-deoxydaunorubicin + NADPH + H+ + O2	DoxA catalyzes three steps in the daunorubicin/doxorubicin biosynthesis pathway: hydroxylation at C13 of 13-deoxycarminomycin and 13-deoxydaunorubicin, oxidation at C-13 of 13-dihydrocarminomycin and daunorubicinol and the hydroxylation at C-14 of daunorubicin. It appears that the primary function of DoxA is to catalyze the enzymatic conversion of 13-deoxydaunorubicin to daunorubicin via daunorubicinol	Streptomyces sp.	13-dihydrodaunorubicin + NADP+ + H2O	-	?
1.14.13.181	13-deoxydaunorubicin + NADPH + H+ + O2	-	Streptomyces sp.	daunorubicinol + NADP+ + H2O	-	?
1.14.13.181	13-dihydrocarminomycin + NADPH + H+ + O2	-	Streptomyces sp.	carminomycin + NADP+ + H2O	-	?
1.14.13.181	13-dihydrocarminomycin + NADPH + H+ + O2	DoxA catalyzes three steps in the daunorubicin/doxorubicin biosynthesis pathway: hydroxylation at C13 of 13-deoxycarminomycin and 13-deoxydaunorubicin, oxidation at C-13 of 13-dihydrocarminomycin and daunorubicinol and the hydroxylation at C-14 of daunorubicin	Streptomyces sp.	carminomycin + NADP+ + H2O	-	?
1.14.13.181	13-dihydrocarminomycin + NADPH + H+ + O2	DoxA catalyzes three steps in the daunorubicin/doxorubicin biosynthesis pathway: hydroxylation at C13 of 13-deoxycarminomycin and 13-deoxydaunorubicin, oxidation at C-13 of 13-dihydrocarminomycin and daunorubicinol and the hydroxylation at C-14 of daunorubicin. It appears that the primary function of DoxA is to catalyze the enzymatic conversion of 13-deoxydaunorubicin to daunorubicin via daunorubicinol	Streptomyces sp.	carminomycin + NADP+ + H2O	-	?

Results 1 - 10 of 23

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Release 2023.1 (January 2023)