EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  1.13.11.86 | 1-hydroxy-2-naphthoate + O2 |
oxidized by MabB at a rate less than 1% of that observed for 5-aminosalicylate |
Comamonas thiooxydans |
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate |
- |
? |
| 1.13.11.86 | 5-aminosalicylate + O2 |
the enzyme participates in the metabolism of 5-aminosalicylate |
Pusillimonas noertemannii |
(2Z,4E)-4-amino-6-oxohepta-2,4-dienedioate |
- |
? |
| 1.13.11.86 | 5-aminosalicylate + O2 |
the enzyme plays an important physiological role in 3-aminobenzoate degradation in Comamonas sp. strain QT12 |
Comamonas thiooxydans |
(2Z,4E)-4-amino-6-oxohepta-2,4-dienedioate |
- |
? |
| 1.13.11.86 | 5-aminosalicylate + O2 |
the enzyme exhibits no activity with gentisate |
Pusillimonas noertemannii |
(2Z,4E)-4-amino-6-oxohepta-2,4-dienedioate |
- |
? |
| 1.13.11.86 | 5-aminosalicylate + O2 |
the two oxygen atoms incorporated into the product are both from the dioxygen molecule. Both 5-aminosalicylate and gentisate can be converted by MabB. The catalytic efficiency of MabB for 5-aminosalicylate is much higher (about 70fold) than that for gentisate |
Comamonas thiooxydans |
(2Z,4E)-4-amino-6-oxohepta-2,4-dienedioate |
- |
? |
| 1.13.11.86 | gentisate + O2 |
the two oxygen atoms incorporated into the product are both from the dioxygen molecule. Both 5-aminosalicylate and gentisate can be converted by MabB. The catalytic efficiency of MabB for 5-aminosalicylate is much higher (about 70fold) than that for gentisate |
Comamonas thiooxydans |
maleylpyruvate |
- |
? |
| 1.13.11.86 | more |
no activity is detected in reaction with salicylate |
Comamonas thiooxydans |
? |
- |
? |
