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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
4.1.3.43
(4R)-4-hydroxy-2-oxohexanoate
reaction catalyzed by BphI variants Y290F, L87N/Y290F and L87W/Y290F
Paraburkholderia xenovorans
pyruvate + propionaldehyde
-
?
4.1.3.43
(4R)-4-hydroxy-2-oxopentanoate
-
Paraburkholderia xenovorans
pyruvate + acetaldehyde
-
?
4.1.3.43
(4S)-4-hydroxy-2-oxohexanoate
double variants L87N/Y290F and L87W/Y290F inactive toward (4S)-4-hydroxy-2-oxohexanoate
Paraburkholderia xenovorans
pyruvate + propionaldehyde
-
?
4.1.3.43
(4S)-4-hydroxy-2-oxopentanoate
-
Paraburkholderia xenovorans
pyruvate + acetaldehyde
-
?
4.1.3.43
(S)-4-hydroxy-2-oxohexanoate
-
Paraburkholderia xenovorans
propanal + pyruvate
-
?
4.1.3.43
4-hydroxy-2-oxoheptanoate
-
Paraburkholderia xenovorans
pyruvate + butanal
-
?
4.1.3.43
4-hydroxy-2-oxohexanoate
4-hydroxy-2-oxohexanoate i.e. HOHA
Paraburkholderia xenovorans
propionaldehyde + pyruvate
-
?
4.1.3.43
4-hydroxy-2-oxohexanoate
-
Paraburkholderia xenovorans
pyruvate + propionaldehyde
-
?
4.1.3.43
4-hydroxy-2-oxopentanoate
4-hydroxy-2-oxopentanoate i.e. HOPA
Paraburkholderia xenovorans
acetaldehyde + pyruvate
-
?
4.1.3.43
4-hydroxy-2-oxopentanoate
-
Paraburkholderia xenovorans
pyruvate + acetaldehyde
-
?
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