EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.1.3.36 | 2-(3-carboxypropyl)-benzoyl-CoA |
- |
Mycobacterium tuberculosis |
? |
- |
? |
4.1.3.36 | 2-succinylbenzoyl-CoA |
- |
Mycobacterium tuberculosis |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoate + CoA |
- |
Escherichia coli |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoate + CoA |
- |
Synechocystis sp. |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoate + CoA |
formation of a structural motif like an oxyanion hole for orientation of the o-succinylbenzoate substrate and stabilization of the oxyanion intermediate in the intramolecular Claisen condensation, which involves a conserved tyrosine residue in the A-loop via induced fit |
Synechocystis sp. |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoate + CoA |
formation of a structural motif like an oxyanion hole for orientation of the o-succinylbenzoate substrate and stabilization of the oxyanion intermediate in the intramolecular Claisen condensation, which involves a conserved tyrosine residue in the A-loop. via induced fit |
Escherichia coli |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoate + CoA |
catalyzes an intramolecular Claisen condensation reaction leading to the formation of 1,4-dihydroxy-2-naphthoyl-CoA from o-succinylbenzoate, the enzyme substrate is chemically unstable |
Mycobacterium tuberculosis |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoate + CoA |
catalyzes an intramolecular Claisen condensation reaction leading to the formation of 1,4-dihydroxy-2-naphthoyl-CoA from o-succinylbenzoate, the enzyme substrate is chemically unstable |
Mycobacterium tuberculosis H37Rv |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoyl-CoA |
- |
Staphylococcus aureus |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |
4.1.3.36 | o-succinylbenzoyl-CoA |
- |
Escherichia coli |
1,4-dihydroxy-2-naphthoyl-CoA + H2O |
- |
? |