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Results 1 - 10 of 24 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
more
overview
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No substrates are Nle11 or Nle12
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relationship between structure and enzyme action
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No substrates are Ala9, Val7
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No substrates are D-Lys11
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specificity depends on the organization of a beta-turn-alpha-helix of nine or more residues containing the basic amino acid doublet near the centre
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No substrates are oxytocin/neurophysin
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structural requirements of the substrate peptides (pro-OT/Np-model)
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No substrates are pro-oxytocin/neurophysin peptides (i.e. pro-OT/Np(1-20)) with D-Arg12
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peptides bearing Nle or D-Arg at subsite P1 or containing Nle or D-Lys at subsite P2 remain uncleaved, substrate bearing the Lys-Arg doublet is hydrolyzed with best efficiency, a minimal length of eight residues is necessary to allow for substrate binding
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Results 1 - 10 of 24 > >>