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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.22.71
DNPNTGDE + H2O
-
Bacillus anthracis
?
-
?
3.4.22.71
IsdC + H2O
IsdC is a surface protein necessary for heme iron uptake in Bacillus anthracis. SrtB recognizes the NPKTG sequence present
Bacillus anthracis
?
-
?
3.4.22.71
more
sortase B may be critical in the early stage of inhaltation anthrax
Bacillus anthracis
?
-
?
3.4.22.71
more
surface protein IsdC and sortase B are required for heme-iron scavenging of Bacillus anthracis
Bacillus anthracis
?
-
?
3.4.22.71
PPKTG + H2O
-
Clostridioides difficile
?
-
?
3.4.22.71
PPKTG + H2O
-
Clostridioides difficile 630
?
-
?
3.4.22.71
Lmo2185 + H2O
-
Listeria monocytogenes
?
-
?
3.4.22.71
Lmo2186 + H2O
NPKSS is a sorting motif of Lmo2186. Recognition of NPKSS by SrtB, even when placed in the context of the heterologous sorting signal of Lmo2185. Proline at position 2, and not lysine at position 3, is essential for the recognition of NPKSS by SrtB
Listeria monocytogenes
?
-
?
3.4.22.71
more
anchoring of SvpA to the bacterial cell wall is specifically mediated by SrzB. The enzyme is involved in the attachment of a subset of proteins to the cell wall, most likely by recognizing an NXZTN sorting motif. SrtB-mediated anchoring can be required to anchor surface proteins involved in the adaption of this microorganism to different environmental conditions
Listeria monocytogenes
?
-
?
3.4.22.71
more
the svpA-srtB locus is regulated by iron availability, mediated by Fur
Listeria monocytogenes
?
-
?
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