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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.22.53
alpha-tubulin + H2O
complete digestion of alpha-tubulin with little effect on beta-tubulin
Allomyces arbusculus
?
-
?
3.4.22.53
benzoyl-Arg p-nitroanilide + H2O
-
Allomyces arbusculus
?
-
?
3.4.22.53
alpha-actin + H2O
slow degradation
Bos taurus
?
-
?
3.4.22.53
casein + H2O
-
Bos taurus
?
-
?
3.4.22.53
IP3R1 + H2O
in presence of Ca2þ, m-calpain cleaves IP3R1 in the endoplasmic lumen
Bos taurus
?
-
?
3.4.22.53
more
no proteolysis of actin
Bos taurus
?
-
?
3.4.22.53
more
the enzyme might be involved in light-dependent regulation of disk membrane morphogenesis by proteolysis of myosin II
Bos taurus
?
-
?
3.4.22.53
more
fetuin A is a potential extracellular regulator of m-calpain at nascent sites of plasma membrane wounding
Bos taurus
?
-
?
3.4.22.53
myosin II heavy chain + H2O
rapid proteolysis
Bos taurus
?
-
?
3.4.22.53
Na+/Ca2+ exchanger + H2O
-
Bos taurus
82000 Da fragment + ?
-
?
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