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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.22.49
cohesin + H2O
-
Arabidopsis thaliana
fragments of cohesin
-
?
3.4.22.49
cohesin + H2O
-
Arabidopsis thaliana
cleaved cohesin
-
?
3.4.22.49
cohesin + H2O
-
Arabidopsis thaliana
?
-
?
3.4.22.49
SYN1 + H2O
the enzyme plays an essential role in embryo development. The enzyme is required for the removal of cohesin from meiotic chromosomes. The cleavage of SYN1 by separase is responsible for the release of sister chromatid cohesion during meiosis
Arabidopsis thaliana
?
-
?
3.4.22.49
cohesin + H2O
-
Caenorhabditis elegans
?
-
?
3.4.22.49
CPAR-1 protein + H2O
-
Caenorhabditis elegans
?
-
?
3.4.22.49
CPAR-1 protein + H2O
separase cleaves the N-tail of the CENP-A related protein CPAR-1 at the meiosis I metaphase-anaphase transition
Caenorhabditis elegans
?
-
?
3.4.22.49
Rec8 + H2O
-
Caenorhabditis elegans
fragments of Rac8
-
?
3.4.22.49
Rec8 + H2O
-
Caenorhabditis elegans
cleaved Rac8
-
?
3.4.22.49
cohesin + H2O
-
Chlamydomonas reinhardtii
?
-
?
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