EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.2.2.6 | more |
the enzyme catalyses the hydrolysis of NAD+ into nicotinamide and ADP-ribose and the formation of cyclic ADP-ribose (cADPR) |
Bos taurus |
? |
- |
? |
3.2.2.6 | more |
selectivity in favor of methanolysis by wild-type enzyme and mutant E138A. 1'-Azido ADP-ribose is the reaction product obtained in the presence of azide. the ADP-ribosyl cyclase activity of wild-type bCD38 isminimal |
Bos taurus |
? |
- |
? |
3.2.2.6 | NAD+ + H2O |
- |
Bos taurus |
ADP-D-ribose + nicotinamide |
- |
? |
3.2.2.6 | NAD+ + H2O |
bovine CD38/NAD+ glycohydrolase catalyzes the hydrolysis of NAD+ to nicotinamide and ADP-ribose and the formation of cyclic ADP-ribose via a stepwise reaction mechanism |
Bos taurus |
ADP-D-ribose + nicotinamide |
- |
? |
3.2.2.6 | NAD+ + H2O |
via a stepwise reaction mechanism |
Bos taurus |
ADP-D-ribose + nicotinamide |
- |
? |
3.2.2.6 | 1,N6-etheno NAD+ + H2O |
- |
Homo sapiens |
epsilon-ADP-ribose + nicotinamide + H+ |
- |
? |
3.2.2.6 | 3-acetylpyridine + adenosine diphosphoribose |
transglycosylation activity, very poor hydrolytic activity with this substrate |
Homo sapiens |
3-acetylpyridine adenine dinucleotide + phosphate |
- |
? |
3.2.2.6 | 3-acetylpyridine adenine dinucleotide + H2O |
- |
Homo sapiens |
? |
- |
? |
3.2.2.6 | 3-acetylpyridine hypoxanthine dinucleotide + H2O |
low activity |
Homo sapiens |
? |
- |
? |
3.2.2.6 | 3-pyridine adenine dinucleotide + H2O |
- |
Homo sapiens |
? |
- |
? |