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Results 1 - 6 of 6
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
D-glycero-beta-D-manno-heptose 1-phosphate + ATP
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ADP-D-glycero-beta-D-manno-heptose + diphosphate
-
?
D-glycero-beta-D-manno-heptose 1-phosphate + ATP
-
ADP-D-glycero-beta-D-manno-heptose + diphosphate
-
?
D-glycero-beta-D-manno-heptose 1-phosphate + ATP
synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase)
ADP-D-glycero-beta-D-manno-heptose + diphosphate
-
?
D-glycero-beta-D-manno-heptose 1-phosphate + ATP
bifunctional D-beta-D-heptose-7-phosphate kinase/D-beta-dheptose-1-phosphate adenylyltransferase. Based on genomic sequence comparisons, bifunctional proteins are predicted to be present in several Gram-negative microorganisms, including Agrobacterium tumefaciens, Buchnera sp., Caulobacter crescentus, Salmonella typhimurium, Salmonella typhi, Vibrio cholerae, Yersinia pestis, Haemophilus influenzae, Helicobacter pylori and Pseudomonas aeruginosa. In contrast, individual genes encoding domains I and II independently are found in Ralstonia eutropha, Neisseria meningitidis and Neisseria gonorrhoeae. In these cases, it is proposed to use the nomenclature hldA and hldC to indicate the individual kinase- and adenylyltransferase-encoding genes, respectively
ADP-D-glycero-beta-D-manno-heptose + diphosphate
-
?
D-glycero-beta-D-manno-heptose 1-phosphate + ATP
no product is obtained when GTP, UTP or CTP is substituted for ATP
ADP-D-glycero-beta-D-manno-heptose + diphosphate
-
?
more
rfaE encodes a bifunctional protein. It is proposed that domain I is involved in the synthesis of D-glycero-D-manno-heptose 1-phosphate, whereas domain II catalyzes the ADP transfer to form ADP-D-glycero-D-manno-heptose
?
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?
Results 1 - 6 of 6