EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.6.1.86 | chorismate + L-glutamine |
- |
Pseudomonas fluorescens |
(2S)-2-amino-4-deoxychorismate + L-glutamate |
- |
? |
2.6.1.86 | chorismate + L-glutamine |
- |
Streptomyces globisporus |
(2S)-2-amino-4-deoxychorismate + L-glutamate |
- |
? |
2.6.1.86 | chorismate + L-glutamine |
the net conversion of chorismate to 3-enolpyruvoylanthranilate by the tandem action of SgcD and SgcG establishes a new branching point in chorismate metabolism leading to synthesis of C-1027, an enediyne antitumor antibiotic |
Streptomyces globisporus |
(2S)-2-amino-4-deoxychorismate + L-glutamate |
- |
? |
2.6.1.86 | chorismate + L-glutamine |
(2S)-2-amino-4-deoxychorismate is formed by a reversible, Mg2+-dependent ADIC synthase activity of anthranilate synthase (EC 4.1.3.27) that can be functionally uncoupled from a Mg2+-dependent ADIC lyase activity of the enzyme by single amino acid substitutions in the TrpE subunit of the anthranilate synthase complex of Salmonella typhimurium |
Salmonella enterica subsp. enterica serovar Typhimurium |
(2S)-2-amino-4-deoxychorismate + L-glutamate |
- |
? |
2.6.1.86 | L-glutamine + chorismate |
- |
Pseudomonas aeruginosa |
(S)-2-amino-2-deoxyisochorismate + glutamate |
- |
? |
2.6.1.86 | L-glutamine + chorismate |
- |
Burkholderia lata |
(S)-2-amino-2-deoxyisochorismate + L-glutamate |
- |
? |
2.6.1.86 | L-glutamine + chorismate |
- |
Burkholderia lata 383 |
(S)-2-amino-2-deoxyisochorismate + L-glutamate |
- |
? |
2.6.1.86 | more |
the enzyme participates in the biosynthesis of phenazine, a precursor for several compounds with antibiotic activity |
Pseudomonas fluorescens |
? |
- |
? |