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Results 1 - 10 of 10
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
more
in vivo reaction is 4'-O-methylation of isoflavones, in vitro reaction is 7-O-methylation
?
-
-
more
in Pisum sativum, there are two highly similar hydroxymaackiain 3-O-methyltransferases HMM, with HMM1 prefering 2,7,4'-trihydroxyisoflavanone as a substrate and HMM2 being the specific O-methyltransferase that methylates (+)-6a-hydroxymaackiain
?
-
-
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
-
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
at 49% of the activity with daidzein, the enzyme also catalyzes the reaction of EC 2.1.1.150
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
isoform HMM1 shows efficiencies for the methylation of 2,7,4'-trihydroxyisoflavanone 4times higher than for the methylation of (+)-6a-hydroxymaackiain, substrate of 6a-hydroxymaackiain-3-O-methyltransferase. Isoform HMM2 has a higher Vmax and lower Km on (+)-6a-hydroxymaackiain, and has a 67fold higher efficiency for the methylation of (+)-6a-hydroxymaackiain than that for 2,7,4'-trihydroxyisoflavanone
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
isoform HMM2, 6a-hydroxymaackiain is the preferred substrate
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
HMM2 is involved primarily in the biosynthesis of (+)-pisatin
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
HMM2 shows efficiencies (relative Vmax/Km) for the 3-O-methylation of (+)-6a-hydroxymaackiain 67 times higher than for the 4'-O-methylation of 2,7,4'-trihydroxyisoflavanone
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-6a-hydroxymaackiain
the bifunctional enzyme also catalyzes the 4'-O-methylation of 2,7,4'-trihydroxyisoflavanonewith slightly higher catalytic efficiency
S-adenosyl-L-homocysteine + (+)-pisatin
-
?
S-adenosyl-L-methionine + (+)-maackiain
at 1.7% of the activity with daidzein, the enzyme also catalyzes the reaction of EC 2.1.1.150
S-adenosyl-L-homocysteine + ?
-
?
Results 1 - 10 of 10