EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   2.1.1.269 | 2-(dimethylsulfonio)propanoate + tetrahydrofolate |
- |
Candidatus Pelagibacter ubique |
2-(methylsulfanyl)propanoate + 5-methyltetrahydrofolate |
- |
? |
| 2.1.1.269 | 2-(dimethylsulfonio)propanoate + tetrahydrofolate |
enzyme exhibits strict substrate specificity for 2-(dimethylsulfonio)propanoate |
Candidatus Pelagibacter ubique |
2-(methylsulfanyl)propanoate + 5-methyltetrahydrofolate |
- |
? |
| 2.1.1.269 | 2-(dimethylsulfonio)propanoate + tetrahydrofolate |
DmdA catalyzes a redox-neutral methyl transfer reaction to produce 5-methyltetrahydrofolate |
Candidatus Pelagibacter ubique |
2-(methylsulfanyl)propanoate + 5-methyltetrahydrofolate |
- |
? |
| 2.1.1.269 | 2-(dimethylsulfonio)propanoate + tetrahydrofolate |
- |
Candidatus Pelagibacter ubique |
2-(methylthio)propanoate + 5-methyltetrahydrofolate |
- |
r |
| 2.1.1.269 | 3-(S,S-dimethylsulfonio)propanoate + tetrahydrofolate |
- |
Candidatus Pelagibacter ubique |
3-(methylthio)propanoate + 5-methyltetrahydrofolate |
- |
? |
| 2.1.1.269 | more |
marine bacterioplankton regulate sulfur flux by converting the precursor dimethylsulfoniopropionate either to dimethylsulfide or to sulfur compounds that are not climatically active |
Candidatus Pelagibacter ubique |
? |
- |
? |
| 2.1.1.269 | more |
no detectable demethylase activity with glycine betaine, dimethyl glycine, methylmercaptopropionate, methionine, or dimethylsulfonioacetate. Less than 1% activity is found with dimethylsulfoniobutanoate and dimethylsulfoniopentanoate |
Candidatus Pelagibacter ubique |
? |
- |
? |
| 2.1.1.269 | more |
strict substrate specificity for dimethylsulfoniopropionate. No detectable demethylase activity with glycine betaine,dimethyl glycine, methylmercaptopropionate, methionine, or dimethylsulfonioacetate and less than 1% activity with dimethylsulfoniobutanoate and dimethylsulfoniopentanoate |
Candidatus Pelagibacter ubique |
? |
- |
? |
| 2.1.1.269 | more |
assay metod, overview. The substrate THF and product 5-methyl-THF are labile under aerobic conditions, oxidation of THF is irreversible and results in the release of 4-aminobenzoyl glutamate, essentially breaking the molecule in half. Half-life of THF in solution at pH 7.0 is about 40 min. DTT can stabilize THF in solution |
Candidatus Pelagibacter ubique |
? |
- |
- |
| 2.1.1.269 | S,S-dimethyl-beta-propiothetin + tetrahydrofolate |
- |
Candidatus Pelagibacter ubique |
3-(methylsulfanyl)propanoate + 5-methyltetrahydrofolate |
- |
? |
