EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.1.1.117 | more |
enzyme catalyzes O-methylation at C-9 and C-2, and O-methylation events occur first at C-9 and then at C-2 |
Stephania intermedia |
? |
- |
- |
2.1.1.117 | more |
enzyme is a scoulerine-9-O-methyltransferase for the biosynthesis of chelerythrine in California poppy, it produces 7-O-methylated, 3'-O-methylated and dual O-methylated products from reticuline and norreticuline, and 9-O-methylated tetrahydrocolumbamine, 2-O-methylscoulerine and tetrahydropalmatine from scoulerine |
Eschscholzia californica subsp. californica |
? |
- |
- |
2.1.1.117 | S-Adenosyl-L-methionine + (R,S)-2,3,9,10-tetrahydroxytetrahydroprotoberberine |
methylated at 50% of the rate of (S)-scoulerine |
Berberis wilsoniae |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + (S)-3,9-dihydroxy-2,10-dimethoxytetrahydroprotoberberine |
methylated at 4% of the rate of (S)-scoulerine |
Berberis wilsoniae |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + (S)-scoulerine |
- |
Berberis stolonifera |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + (S)-scoulerine |
the enzyme is responsible for a late step in the biosynthesis of berberine |
Coptis japonica |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + (S)-scoulerine |
central role in orotoberberine biosynthesis |
Berberis wilsoniae |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + 6-O-methylnorlaudanosoline |
8% of the activity relative to (S)-scoulerine |
Coptis japonica |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + norlaudanosoline |
2% of the activity relative to (S)-scoulerine |
Coptis japonica |
? |
- |
? |
2.1.1.117 | S-Adenosyl-L-methionine + norreticuline |
9% of the activity relative to (S)-scoulerine |
Coptis japonica |
? |
- |
? |