EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
  1.8.1.10 | CoA disulfide + NADPH |
substrate CoASSCoA, enzyme forms during catalysis a stable mixed disulfide intermediate with CoA |
Staphylococcus aureus |
CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA disulfide + NADPH |
central role in thiol metabolism |
Staphylococcus aureus |
CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA disulfide + NADPH |
substrate CoASSCoA, enzyme forms during catalysis a stable mixed disulfide intermediate with CoA |
Staphylococcus aureus NCTC 8325 |
CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA disulfide + NADPH |
central role in thiol metabolism |
Staphylococcus aureus NCTC 8325 |
CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA-glutathione + NADPH |
- |
Rattus norvegicus |
glutathione + CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA-glutathione + NADPH |
high substrate specificity |
Rattus norvegicus |
glutathione + CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA-glutathione + NADPH |
may be important in metabolism of CoASSG |
Rattus norvegicus |
glutathione + CoA + NADP+ |
- |
? |
| 1.8.1.10 | CoA-glutathione + NADPH |
metabolism of CoA-glutathione disulfide, role may be to replenish the CoA pool from CoAS-SG formed either chemically or enzymatically during cell growth, accumulation of CoAS-SG in vivo in spite of high enzyme levels indicates involvement of a control mechanism |
Escherichia coli |
glutathione + CoA + NADP+ |
- |
? |
| 1.8.1.10 | more |
no reduction of disulfides such as cystine, cystamine, panthetine, and insulin |
Rattus norvegicus |
? |
- |
? |
| 1.8.1.10 | more |
no reduction of CoASSCys, GSSCys or CysSSCys |
Saccharomyces cerevisiae |
? |
- |
? |
