EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.2.1.80 | more |
does not reduce acyl-CoA |
Synechococcus elongatus |
? |
- |
? |
1.2.1.80 | more |
because of technical difficulties in preparing the native substrates for CpFAS1-R, which are very long chain fatty acyl-ACPs, long chain and very long chain fatty acyl-CoAs are used as substrates to assay CpFAS1-R activity |
Cryptosporidium parvum |
? |
- |
? |
1.2.1.80 | more |
in Saccharomyces cerevisiae overexpressed truncated version of AtFAR6, which lacks the N-terminal extension, produces C16:0 primary fatty alcohol as well as C18:0 fatty alcohols much more efficiently than the full length protein |
Arabidopsis thaliana |
? |
- |
? |
1.2.1.80 | more |
does not reduce acyl-CoA |
Synechococcus elongatus PCC 7942 |
? |
- |
? |
1.2.1.80 | a long-chain aldehyde + an [acyl-carrier protein] + NAD(P)+ |
- |
Synechococcus elongatus |
a long-chain acyl-[acyl-carrier protein] + NAD(P)H + H+ |
- |
? |
1.2.1.80 | fatty acyl-[acyl carrier protein] + NAD(P)H + H+ |
kinetically preferred and likely the in vivo substrate |
Synechococcus elongatus |
fatty aldehyde + acyl carrier protein + NAD(P)+ |
- |
? |
1.2.1.80 | fatty acyl-[acyl carrier protein] + NAD(P)H + H+ |
kinetically preferred and likely the in vivo substrate |
Synechococcus elongatus PCC 7942 |
fatty aldehyde + acyl carrier protein + NAD(P)+ |
- |
? |
1.2.1.80 | fatty acyl-[acyl-carrier protein] + NAD(P)H + H+ |
- |
Cryptosporidium parvum |
fatty aldehyde + acyl-carrier protein + NAD(P)+ |
- |
? |
1.2.1.80 | fatty acyl-CoA + NAD(P)H + H+ |
CpFAS1-R can only utilize very long chain fatty acyl-CoAs as substrates, with activity on C26 > C24 > C22 > C20, but no activity on C18 and C16 or fewer carbons |
Cryptosporidium parvum |
fatty aldehyde + CoA + NAD(P)+ |
since aldehydes are toxic to cells it is very likely that the fatty aldehyde is immediately transformed into the corresponding alcohol by the enzyme complex |
? |
1.2.1.80 | hexacosanoyl-CoA + NAD(P)H + H+ |
- |
Cryptosporidium parvum |
hexacosanal + CoA + NAD(P)+ |
- |
? |