EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.99.4 | progesterone + NADPH + H+ + O2 |
- |
Amorphotheca resinae |
Testosterone acetate + NADP+ + H2O |
- |
? |
1.14.99.4 | progesterone + NADPH + H+ + O2 |
- |
Chlorocebus aethiops |
Testosterone acetate + NADP+ + H2O |
- |
? |
1.14.99.4 | progesterone + NADPH + H+ + O2 |
- |
Ictalurus punctatus |
Testosterone acetate + NADP+ + H2O |
- |
? |
1.14.99.4 | testosterone + NADPH + O2 |
- |
Ictalurus punctatus |
6beta-hydroxytestosterone + NADP+ + H2O |
- |
? |
1.14.99.4 | 16alpha,17alpha-oxidopregn-4-ene-3,20-dione + NADPH + O2 |
degradation of pregnane side chains |
Ilyonectria destructans |
16alpha-hydroxyandrost-4-ene-3,17-dione |
- |
? |
1.14.99.4 | 17alpha-hydroxypregn-4-ene-3,20-dione + NADPH + O2 |
degradation of pregnane side chains, about 210% the rate of the reaction with progesterone |
Ilyonectria destructans |
androst-4-ene-3,17-dione + NADP+ + ? |
- |
? |
1.14.99.4 | 17alpha-methylpregn-4-ene-3,20-dione + NADPH + O2 |
about 4.3% the rate of the reaction with progesterone |
Ilyonectria destructans |
? |
- |
? |
1.14.99.4 | deoxycorticosterone + NADPH + O2 |
degradation of pregnane side chains, about 64% the rate of the reaction with progesterone |
Ilyonectria destructans |
testosterone + NADP+ + ? |
- |
? |
1.14.99.4 | more |
cortisol, 20alpha-hydroxy-16alpha,17alpha-oxidopregn-4-ene-3,20-dione and 20beta-hydroxypregn-4-ene-3-one are no substrates |
Ilyonectria destructans |
? |
- |
? |
1.14.99.4 | pregna-4,16-diene-3,20-dione + NADPH + O2 |
degradation of pregnane side chains, about 104% the rate of the reaction with progesterone |
Ilyonectria destructans |
androst-4-ene-3,17-dione |
- |
? |