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Results 1 - 10 of 81 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid + AH2 + O2
-
? + A + H2O
-
-
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid + AH2 + O2
-
? + A + H2O
-
-
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid + AH2 + O2
the substrate is bound in the cyclooxygenase channel of COX-2, binding structure, overview. The carboxylate of docosahexaenoate interacts with Arg120 and Tyr355 at the base of the channel and the omega-end abuts the side chain of Ile377 near Gly533 in the hydrophobic groove above Ser530
? + A + H2O
-
?
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoic acid + AH2 + O2
substrate binding structure and nonproductive conformation, overview
? + A + H2O
-
?
8,11,14-eicosatrienoic acid + O2
-
prostaglandin G1 + ?
-
?
8,11,14-eicosatrienoic acid + O2
bis-dioxygenase activity, cyclooxygenase activity, presence of hematin
prostaglandin G1 + ?
9alpha,11alpha-epidioxy-15(S)-hydroperoxy-13-trans-prostenoic acid
?
8,11,14-eicosatrienoic acid + O2
-
prostaglandin H1 + ?
-
-
8,11,14-eicosatrienoic acid + O2
hydroperoxidase activity, presence of hematin and tryptophan
prostaglandin H1 + ?
-
?
arachidonate + 2 O2
-
prostaglandin G2
-
?
arachidonate + AH2 + 2 O2
-
prostaglandin G2 + A + H2O
-
?
Results 1 - 10 of 81 > >>