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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.1.1.254
(S)-carnitine + NAD+
-
Agrobacterium tumefaciens
3-dehydrocarnitine + NADH + H+
-
?
1.1.1.254
(S)-carnitine + NAD+
-
Agrobacterium sp.
3-dehydrocarnitine + NADH + H+
-
?
1.1.1.254
(S)-carnitine + NAD+
r
Agrobacterium sp.
3-dehydrocarnitine + NADH + H+
-
?
1.1.1.254
(S)-carnitine + NAD+
substrate is derived as a waste product from chemical production procedures of L(-)-carnitine
Agrobacterium tumefaciens
3-dehydrocarnitine + NADH + H+
formation of poly-beta-hydroxybutyrate as a storage product
?
1.1.1.254
3-hydroxy-2-butanone + NAD+
enzyme specific for D-carnitine
Agrobacterium sp. 525a
2,3-butandione + NADH
-
?
1.1.1.254
DL-4-amino-3-hydroxy-n-butyrate + NAD+
D-carnitine dehydrogenase
Agrobacterium sp. 525a
DL-4-amino-3-keto-n-butyrate + NADH
-
?
1.1.1.254
DL-4-amino-3-hydroxy-n-butyrate + NAD+
D-carnitine dehydrogenase, less than 20% velocity compared to D-carnitine
Agrobacterium sp.
DL-4-amino-3-keto-n-butyrate + NADH
-
?
1.1.1.254
more
initial step of D(+)-carnitine degradation
Agrobacterium sp.
?
-
?
1.1.1.254
more
it is expected that D-carnitine can be converted into L-carnitine by coupling reactions of D-carnitine dehydrogenase and L-carnitine dehydrogenase
Agrobacterium sp.
?
-
?
1.1.1.254
more
enzyme is induced during growth on D-carnitine
Agrobacterium sp.
?
-
?
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